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Letrozole is a medication that is used in: • Adjuvant treatment of women after menopause who have developed early breast cancer that is hormone positive. • Adjuvant treatment of women after menopause who have developed early breast cancer and were previously receiving adjuvant treatment with tamoxifen. • First and second line treatment of women after menopause with unknown advanced breast cancer or hormone positive breast cancer. Do not take Letrozole : • If you are allergic to Letrozole or any of the ingredients in this medicine. Tell your doctor about the allergy and what signs you had. • If you have not reached menopause yet. • If you are pregnant. Warnings and Precautions : • Talk to your doctor or pharmacist if you develop allergic reactions such as shortness of breath- skin rash- swelling of the face or neck- decreased blood pressure and dizziness. • This medication may affect your bone density. Your doctor may recommend bone density monitoring. • This medication may increase your total cholesterol. Your doctor may recommend cholesterol monitoring. • This medication may cause fatigue- drowsiness and dizziness. Do not drive or use machinery if you are not feeling well. Possible side effects of Letrozole : Possible side effects of Letrozole include allergic reaction- hot flashes- joint pain- flushing- weakness- edema- headache- dizziness- elevated cholesterol levels- sweating and bone pain. Other medicines and Letrozole : Tell your doctor or pharmacist if you are taking- have recently taken or might take any other medications. Tell your doctor if you are taking tamoxifen (breast cancer medication). How to take Letrozole : Postmenopausal women: Recommended dose is 2.5 mg orally once daily. Patients with cirrhosis (advanced liver disease) or severe liver impairment: Recommended dose is 2.5 mg orally every other day. • Take tablets with or without meals. • Take tablet with a full glass of water. How to store Letrozole : • Store at 20 to 25°C (68 to 77°F) • Keep out of the reach of children and pets • Do not use beyond the expiry date mentioned on the box • Keep medication in its original pack to protect it from moisture • Do not use damaged pills • Do not dispose pills in the wastewater or household waste